DelveInsight’s “Eosinophilic Esophagitis Market Insight, Epidemiology, and Market Forecast – 2034” report delivers an in-depth understanding of the Eosinophilic Esophagitis historical and forecasted epidemiology as well as the Eosinophilic Esophagitis market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
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Key Takeaways from the Eosinophilic Esophagitis Market Report
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Eosinophilic Esophagitis Epidemiology Segmentation in the 7MM
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Eosinophilic Esophagitis Marketed Drugs
DUPIXENT, which was invented using Regeneron’s proprietary VelocImmune technology, is a fully human monoclonal antibody that inhibits the signaling of the Interleukin-4 (IL-4) and Interleukin-13 (IL-13) pathways and is not an immunosuppressant. It is approved for the treatment of DUPIXENT, which was invented using Regeneron’s proprietary VelocImmune technology, is a fully human monoclonal antibody that inhibits the signaling of the Interleukin-4 (IL-4) and Interleukin-13 (IL-13) pathways and is not an immunosuppressant.
Eosinophilic Esophagitis Emerging Drugs
Cendakimab/RPC4046/CC-93538 is a recombinant humanized, high affinity, selective, anti-IL-13 mAb. RPC4046 binds an IL-13 epitope that prevents its binding to both IL-13R (alpha) 1 and IL-13R (alpha) 2, providing potential efficacy and/or safety advantages. The drug has been granted ODD for the treatment of EoE by the US FDA. In the Phase II study, RPC4046 demonstrated positive results. Currently, the company is conducting two Phase III Eosinophilic Esophagitis clinical trials to evaluate the efficacy and safety of CC-93538 in adult and adolescent participants with EoE.
TEZSPIRE (tezepelumab) is being developed by AstraZeneca in collaboration with Amgen as a first-in-class human monoclonal antibody that inhibits the action of TSLP. This key epithelial cytokine sits at the top of multiple inflammatory cascades. It is critical in the initiation and persistence of allergic, eosinophilic, and other types of airway inflammation associated with severe asthma, including airway hyperresponsiveness. TEZSPIRE acts at the top of the inflammation cascade and has the potential to help address a broad population of severe asthma patients irrespective of biomarker levels.
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Eosinophilic Esophagitis Market Outlook
The Eosinophilic Esophagitis Market is driven by significant unmet needs, particularly in the development of novel treatments and the establishment of comprehensive guidelines for adolescents and adults. Current treatments, like proton pump inhibitors and corticosteroids therapy, manage symptoms but come with serious side effects due to high steroid dosages. Although in recent years therapies like DUPIXENT, EOHILIA and JOrveza got approved in 7MM countries but still there is huge scope for emerging.
Eosinophilic Esophagitis Companies
Bristol Myers Squibb (BMS), Ellodi Pharmaceuticals, AstraZeneca, Kyowa Hakko Kirin, Dr. Falk Pharma GmbH, Regeneron Pharmaceuticals, Sanofi, Allakos, Pfizer, Revolo Biotherapeutics, EsoCap AG, and others.
Scope of the Eosinophilic Esophagitis Market Report
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Table of Contents
1. Key Insights
2. Eosinophilic Esophagitis Market Report Introduction
3. Eosinophilic Esophagitis Market Overview at a Glance
4. Eosinophilic Esophagitis Methodology
5. Eosinophilic Esophagitis Executive Summary
6. Key Events
7. Disease Background and Overview
8. Eosinophilic Esophagitis Treatment
9. Treatment Guidelines
10. Eosinophilic Esophagitis Epidemiology and Patient Population
11. Patient Journey
12. Eosinophilic Esophagitis Marketed Therapies
13. Eosinophilic Esophagitis Emerging Therapies
14. Eosinophilic Esophagitis Market Analysis
15. KOL Views
16. Eosinophilic Esophagitis SWOT Analysis
17. Eosinophilic Esophagitis Unmet Needs
18. Market Access and Reimbursement
19. Appendix
20. DelveInsight Capabilities
21. Disclaimer
About Us
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