(Albany, US) DelveInsight has launched a new report on Cystic Fibrosis Epidemiology
DelveInsight’s ‘Cystic Fibrosis Epidemiology Forecast – 2030’ report delivers an in-depth understanding of the Cystic Fibrosis (CF), historical and forecasted epidemiology in the United States, and EU5 (Germany, Spain, Italy, France, and the United Kingdom).
According to the Cystic Fibrosis Foundation, “Cystic Fibrosis is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe over time”. In people with CF, a defective gene causes a thick, sticky buildup of mucus in the lungs, pancreas, and other organs. In the lungs, the mucus clogs the airways and traps bacteria leading to infections, extensive lung damage, and eventually respiratory failure. In the pancreas, the mucus prevents the release of digestive enzymes that allow the body to break down food and absorb vital nutrients. CFTR, the gene associated with cystic fibrosis, encodes the protein cystic fibrosis transmembrane conductance regulator. The gene was identified in 1989 and is found at 7q31.2, the long arm (q) of chromosome 7 at position 31.2. Survival has increased for patients with cystic fibrosis from late teens to mid-30s because of the many advances in diagnosis and treatment, and in some instances, lung transplantation.
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Cystic Fibrosis Epidemiology
More than 1000 possible changes can occur in CFTR to cause cystic fibrosis, but approximately 70% of all patients with cystic fibrosis have the same defect: F508. This defect is a deletion of 3 bases that causes the loss of the protein phenylalanine. Patients who have a complete loss of the CFTR gene have a clinical phenotype representative of pancreatic disease, severe pulmonary disease, gastrointestinal problems, and infertility (in men) or, sometimes, fertility problems. The Cystic Fibrosis (CF) epidemiology division provides insights about the historical and current patient pool along with the forecasted trend for every seven major countries. It helps recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the report also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Key facts of the report
Cystic Fibrosis Report Scope
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Table of content
1 Key Insights
2 Executive Summary
3 Organizations
4 Epidemiology and Market Methodology
5 Cystic Fibrosis: Market Overview at a Glance
6 Cystic Fibrosis: Market Overview at a Glance
7 Epidemiology and Patient Population
8 Treatment for Cystic Fibrosis
9 KOL Views
10 Appendix
11 DelveInsight Capabilities
12 Disclaimer
13 About DelveInsight
Why should you buy this report?
The Cystic Fibrosis (CF) Epidemiology report will allow the user to –
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