Gurugram, India (September 02, 2026): DelveInsight’s “Liver Cirrhosis Pipeline Insight 2026” report provides comprehensive insights about 30+ companies and 30+ pipeline drugs in the Liver Cirrhosis Pipeline landscape. It covers the Liver Cirrhosis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Liver Cirrhosis therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the Liver Cirrhosis Pipeline Report
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Liver Cirrhosis Overview
Liver cirrhosis is a condition in which the liver is scarred and permanently damaged, and scar tissue replaces healthy liver tissue, preventing the liver from working normally. Cirrhosis is usually caused by long-term liver damage from conditions such as alcohol-associated liver disease, nonalcoholic fatty liver disease, chronic hepatitis C, and chronic hepatitis B. Symptoms of cirrhosis may not appear until the liver is badly damaged and can include fatigue, severe itchy skin, and swelling in the legs and abdomen. Doctors diagnose cirrhosis based on medical history, a physical exam, and the results of tests such as blood tests, imaging tests, and liver biopsy. There is no specific cure for cirrhosis, but treating the underlying causes of cirrhosis may keep it from getting worse and may help prevent liver failure. Complications of cirrhosis can include portal hypertension, infections, and liver cancer. Eating a healthy diet and avoiding foods and drinks that can damage the liver, such as raw shellfish and alcohol, can help manage cirrhosis. In some cases, liver transplant may be an option.
Liver Cirrhosis Emerging Drugs Profile
Elafibranor (GFT-505) is under development for the treatment of colitis, non-alcoholic fatty liver disease, primary biliary cholangitis (PBC), and primary sclerosing cholangitis. The drug candidate is administered orally as a coated tablet. It acts by targeting peroxisome proliferator-activated receptor (PPAR) alpha and PPAR-beta / PPAR- delta. The drug candidate was under development for dyslipidemia, abdominal obesity, type 2 diabetes, Crohn’s disease, insulin resistance and glucose intolerance, colitis and NAFLD/NASH-induced hepatocellular carcinoma (HCC). Currently, the drug is in phase III stage of its clinical trial.
AZD2389 is a hepatoprotectant small molecule developed by AstraZeneca. It is designed to provide protection to the liver. The drug is part of a class aimed at treating liver-related diseases or conditions. Currently, the drug is in Phase II stage of its clinical trial for the treatment of liver Cirrhosis.
PHIN-214 is an investigational drug currently undergoing Phase Ib safety trials by harmaIN, aimed at treating refractory ascites, a condition for which no FDA-approved pharmacological therapy currently exists. Its mechanism of action (MOA) involves targeting and shutting down the Renin-Angiotensin-Aldosterone System (RAAS) signaling pathway, which plays a key role in the retention of excess salt and water by the kidneys. By inhibiting this pathway, PHIN-214 seeks to prevent the accumulation of ascitic fluid, offering potential therapeutic benefits for patients with liver disease who no longer respond to diuretic treatments.
The Liver Cirrhosis pipeline report provides insights into
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Liver Cirrhosis Companies
Versantis AG, Mirum Pharmaceuticals, Sagimet Biosciences, TenNor Therapeutics, Prism Pharma, Vedanta Biosciences, Lipocine, Gwo Xi Stem Cell Applied Technology, Galectin Therapeutics, Resolution Therapeutics, Ipsen, and AstraZeneca and others.
Liver Cirrhosis Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Liver Cirrhosis Products have been categorized under various Molecule types such as
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Scope of the Liver Cirrhosis Pipeline Report
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Table of Content
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